P53 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | P53 |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human, African Green monkey |
| Isotype | IgG1,k |
| Format | unconjugated |
| Size | 0.05 mL, 0.2 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This P53 antibody is generated from a mouse immunized with a recombinant protein conjugated synthetic peptide between 1-393 amino acids from human P53. Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. In cooperation with mitochondrial PPIF is involved in activating oxidative stress-induce |
| Immunogen | n/a |
| Other Names | [Cellular tumor antigen p53; Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53; TP53; P53] |
| Gene, Accession # | [TP53], Gene ID: 7157, NCBI: NP_000537.3, UniProt: P04637 |
| Catalog # | MBS9217067 |
| Price | $165, $370 |
| Order / More Info | P53 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Zakut-Houri R.,et al.EMBO J. 4:1251-1255 (1985). Lamb P.,et al.Mol. Cell. Biol. 6:1379-1385 (1986). Harlow E.,et al.Mol. Cell. Biol. 5:1601-1610 (1985). Harris N.,et al.Mol. Cell. Biol. 6:4650-4656 (1986). Buchman V.L.,et al.Gene 70:245-252 (1988). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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