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Antigenic Specificity | STEA3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total STEA3 protein. Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe3+ to Fe2+. Can also reduce of Cu2+ to Cu1+, suggesting that it participates in copper homeostasis. Uses NADP+ as acceptor. May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP.Passer B.J., Proc. Natl. Acad. Sci. U.S.A. 100:2284-2289(2003).Korkmaz C.G., Oncogene 24:4934-4945(2005).Steiner M.S., Cancer Res. 60:4419-4425(2000). |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human STEA3. |
Other Names | [Metalloreductase STEAP3; EC 1.16.1.-; Six-transmembrane epithelial antigen of prostate 3; Tumor suppressor-activated pathway protein 6; hTSAP6] |
Gene, Accession # | [STEA3], Gene ID: 55240, NCBI: NP_001008410.1, UniProt: Q658P3 |
Catalog # | MBS9403783 |
Price | $200, $255 |
Order / More Info | STEA3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |