STEA3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySTEA3
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB), Immunofluorescence (IF)
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DescriptionThe antibody detects endogenous levels of total STEA3 protein. Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe3+ to Fe2+. Can also reduce of Cu2+ to Cu1+, suggesting that it participates in copper homeostasis. Uses NADP+ as acceptor. May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP.Passer B.J., Proc. Natl. Acad. Sci. U.S.A. 100:2284-2289(2003).Korkmaz C.G., Oncogene 24:4934-4945(2005).Steiner M.S., Cancer Res. 60:4419-4425(2000).
ImmunogenImmunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human STEA3.
Other Names[Metalloreductase STEAP3; EC 1.16.1.-; Six-transmembrane epithelial antigen of prostate 3; Tumor suppressor-activated pathway protein 6; hTSAP6]
Gene, Accession #[STEA3], Gene ID: 55240, NCBI: NP_001008410.1, UniProt: Q658P3
Catalog #MBS9403783
Price$200, $255
Order / More InfoSTEA3 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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