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Antigenic Specificity | ITGA2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix.(Microbial infection) Integrin ITGA2:ITGB1 acts as a receptor for human rotavirus A (PubMed:12941907). Integrin ITGA2:ITGB1 acts as a receptor for human echoviruses 1 and 8 (PubMed:8411387). |
Immunogen | Immunogen: Recombinant protein of human ITGA2 |
Other Names | [BR; GPIa; CD49B; HPA-5; VLA-2; VLAA2] |
Gene, Accession # | [ITGA2], Gene ID: 3673, NCBI: NP_002194.2, UniProt: P17301 |
Catalog # | MBS8546924 |
Price | $280 |
Order / More Info | ITGA2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |