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Antigenic Specificity | CBL |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for E3 ubiquitin-protein ligase CBL(CBL) detection. Tested with WB in Human, Mouse, Rat. Background: CBL(Cbl proto-oncogene) is also known as C-CBL, RNF55, CBL2 and E3 ubiquitin protein ligase. Wei et al.(1990) mapped the CBL gene to chromosome 11q23.3-qter by molecular characterization of the breakpoints in 2 somatic cell hybrids. The encoded protein is one of the enzymes required for targeting substrates for degradation by the proteasome. This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes(E2) to specific substrates. This protein also contains an N-terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine-phosphorylated substrates an |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human CBL (863-877aa NLMSQGYSYQDIQKA), identical to the related rat and mouse sequences. |
Other Names | [E3 ubiquitin-protein ligase CBL; Cbl proto-oncogene, E3 ubiquitin protein ligase; 4732447J05Rik; C CBL; Cas Br M(murine) ecotropic retroviral transforming sequence; Cas-Br-M(murine) ecotropic retroviral transforming sequence; Casitas B lineage lymphoma proto oncogene; Casitas B-lineage lymphoma proto-oncogene; CBL 2; cbl; CBL_HUMAN; CBL2; E3 ubiquitin protein ligase CBL; E3 ubiquitin-protein ligase CBL; Oncogene CBL2; Proto oncogene c CBL; Proto-oncogene c-CBL; RGD1561386; RING finger protein 55; RNF55; Signal transduction protein CBL], [CBL; CBL; CBL2; NSLL; C-CBL; RNF55; FRA11B; CBL2; RNF55] |
Gene, Accession # | [CBL], Gene ID: 867, NCBI: P22681.2, UniProt: P22681 |
Catalog # | MBS176320 |
Price | $280 |
Order / More Info | CBL Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |