CBL Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCBL
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionDescription: Rabbit IgG polyclonal antibody for E3 ubiquitin-protein ligase CBL(CBL) detection. Tested with WB in Human, Mouse, Rat. Background: CBL(Cbl proto-oncogene) is also known as C-CBL, RNF55, CBL2 and E3 ubiquitin protein ligase. Wei et al.(1990) mapped the CBL gene to chromosome 11q23.3-qter by molecular characterization of the breakpoints in 2 somatic cell hybrids. The encoded protein is one of the enzymes required for targeting substrates for degradation by the proteasome. This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes(E2) to specific substrates. This protein also contains an N-terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine-phosphorylated substrates an
ImmunogenImmunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human CBL (863-877aa NLMSQGYSYQDIQKA), identical to the related rat and mouse sequences.
Other Names[E3 ubiquitin-protein ligase CBL; Cbl proto-oncogene, E3 ubiquitin protein ligase; 4732447J05Rik; C CBL; Cas Br M(murine) ecotropic retroviral transforming sequence; Cas-Br-M(murine) ecotropic retroviral transforming sequence; Casitas B lineage lymphoma proto oncogene; Casitas B-lineage lymphoma proto-oncogene; CBL 2; cbl; CBL_HUMAN; CBL2; E3 ubiquitin protein ligase CBL; E3 ubiquitin-protein ligase CBL; Oncogene CBL2; Proto oncogene c CBL; Proto-oncogene c-CBL; RGD1561386; RING finger protein 55; RNF55; Signal transduction protein CBL], [CBL; CBL; CBL2; NSLL; C-CBL; RNF55; FRA11B; CBL2; RNF55]
Gene, Accession #[CBL], Gene ID: 867, NCBI: P22681.2, UniProt: P22681
Catalog #MBS176320
Price$280
Order / More InfoCBL Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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