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Antigenic Specificity | Phospho-DNAJC2/MPP11 (Ser49) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mousepredicted: porcine, bovine, horse, sheep, rabbit, chicken, Xenopus |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Peptide ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-DNAJC2/MPP11 (Ser49) Antibody detects endogenous levels of DNAJC2/MPP11 only when phosphorylated at Ser49. Description: Acts both as a chaperone in the cytosol and as a chromatin regulator in the nucleus. When cytosolic, acts as a molecular chaperone: component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, stimulates the ATPase activity of the ribosome-associated pool of Hsp70-type chaperones HSPA14 that bind to the nascent polypeptide chain. When nuclear, mediates the switching from polycomb-repressed genes to an active state: specifically recruited at histone H2A ubiquitinated at 'Lys-119' (H2AK119ub), and p |
Immunogen | Immunogen: A synthesized peptide derived from human DNAJC2/MPP11 around the phosphorylation site of Ser49. Tissue Specificity: Widely expressed. |
Other Names | [AU020218; DnaJ (Hsp40) homolog subfamily C member 2; DnaJ homolog subfamily C member 2; Dnajc2; DNJC2_HUMAN; M phase phosphoprotein 11; M-phase phosphoprotein 11; MGC105894; MIDA1; MPHOSPH11; MPP11; OTTMUSP00000031226; ZRF1; Zrf2; ZUO1; Zuotin related factor 1; Zuotin related factor 2; Zuotin-related factor 1] |
Gene, Accession # | [DNAJC2/MPP11], Gene ID: 27000, NCBI: Q99543.4, UniProt: Q99543 |
Catalog # | MBS9610796 |
Price | $225, $280, $340 |
Order / More Info | Phospho-DNAJC2/MPP11 (Ser49) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |