FOXP3 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | FOXP3 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | epitope affinity purified |
| Size | 0.1 mg |
| Concentration | Size: 100 ug/200 ul |
| Applications | ELISA, Western Blot, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody recognizes ~52 kDa of FOXP3 protein. It reacts to human, mouse and rat. The other species are not tested. Forkhead/winged-helix box (Fox) genes are the transcriptional regulators and highly conserved across mammals. It contains a FOX DNA-binding domain and large polyglutamine tract. The FOXPs are involved in organogenesis and cell differentiation. FOXP3 is essential for normal immune homeostasis. FOXP3 is stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, at low level in CD4 positive/CD25 negative cells, and is absent in CD4 negative/CD8 positive T cells. FOXP3 may be a master regulatory gene and a more specific marker of regulatory T cells than other T cells. |
| Immunogen | Antigen Preparation: A synthetic peptide corresponding to the C-terminus of human FOXP3 protein. This sequence is identical within human, mouse, rat origins. |
| Other Names | [Rabbit FOXP3; FOXP3; forkhead box P3; JM2; AIID; IPEX; PIDX; XPID; DIETER; SCURFIN; scurfin; JM2 protein; immunodeficiency; polyendocrinopathy; enteropathy; X-linked; immune dysregulation; polyendocrinopathy; enteropathy; X-linked], [FOXP3; FOXP3; JM2; AIID; IPEX; PIDX; XPID; DIETER; MGC141961; MGC141963; IPEX] |
| Gene, Accession # | [FOXP3], Gene ID: 50943, NCBI: NP_001107849.1, UniProt: Q9BZS1 |
| Catalog # | MBS462166 |
| Price | $265 |
| Order / More Info | FOXP3 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Rao et al. Differentiation and expansion of T cells with regulatory function from human peripheral lymphocytes by stimulation in the presence of TGF-{beta}. J Immunol. 2005 Feb 1;174 (3):1446-55. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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