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Antigenic Specificity | P2RX7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for P2X purinoceptor 7(P2RX7) detection. Tested with WB in Human, Mouse, Rat. Background: P2X purinoceptor 7, also called P2X7, is a protein that in humans is encoded by the P2RX7 gene. The product of this gene belongs to the family of purnoceptors for ATP. P2RX7 was mapped to chromosome 12q24 by fluorescence in situ hybridization. It is a receptor for ATP that acts as a ligand-gated ion channel. This gene is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. It could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells. |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of rat P2RX7 (1-20aa MPACCSWNDVFQYETNKVTR), different from the related mouse sequence by one amino acid, and from the related human sequence by two amino acids. |
Other Names | [P2X purinoceptor 7; purinergic receptor P2X, ligand-gated ion channel, 7; ATP receptor; P2X purinoceptor 7; P2X7; P2Z receptor; Purinergic receptor; purinergic receptor P2X, ligand gated ion channel, 7], [P2rx7; P2rx7; P2X7] |
Gene, Accession # | [P2RX7], Gene ID: 29665, NCBI: Q64663.1, UniProt: Q64663 |
Catalog # | MBS176306 |
Price | $280 |
Order / More Info | P2RX7 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |