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Antigenic Specificity | CD27 |
Clone | [LG.3A10] |
Host Species | Hamster |
Reactive Species | human, rat |
Isotype | IgG |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 500 ug/ml |
Applications | Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Mouse CD27. The LG.3A10 monoclonal antibody reacts with mouse CD27, a lymphocyte-specific member of the TNFR superfamily. CD27 is expressed by virtually all mature T cells and by a subpopulation of B cells, mainly memory B cells. In mouse, CD27 has been found on nearly all thymocytes excluding a population of CD46-CD8-precursors. CD27 binds to CD70 and, through this interaction, plays an important role in T cell-B cell interaction. It has been reported that triggering CD27 plays an important role in the maturation of CD4+ and CD8+ effector cells. LG.8F10 cross-reacts with human and rat CD27.When the monoclonal antibody LG.3A10 is crosslinked on purified T cells, proliferation is increased. In the absence of crosslinking, the an |
Immunogen | n/a |
Other Names | [Armenian Hamster CD27; CD27; CD27; CD27; CD 27; TNFRSF7; CD-27; T14; CD 27; CD-27] |
Gene, Accession # | [CD27], Gene ID: 939, NCBI: NP_001233.1, UniProt: P26842 |
Catalog # | MBS5309240 |
Price | $250 |
Order / More Info | CD27 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |