Human CD49f Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman CD49f
Clone[4F10]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2b
Formatunconjugated
Size100 tests
Concentrationn/a
ApplicationsFlow Cytometry, Immunoprecipitation, Immunohistochemistry (Frozen sections)
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DescriptionSpecificity: Human CD49f. CD49f is the 150 kDa integrin alpha6 chain which associates noncovalently with the integrin beta1 subunit (CD29) and with the integrin beta4 (CD104) chain to form, respectively, the very late antigen-6 (VLA-6) and alpha6beta4 integrin heterodimers. VLA-6 is expressed on thymocytes, T lymphocytes, monocytes and platelets. CD49f/CD29 expression is upregulated on activated T lymphocytes and memory T cells. VLA-6 serves as the laminin receptor on platelets, monocytes and T cells. VLA-6-mediated binding to laminin provides a costimulatory signal to T cells for activation and proliferation.1-3.
Immunogenn/a
Other Namesn/a
Gene, Accession #n/a
Catalog #MBS670277
Price$380
Order / More InfoHuman CD49f Antibody from MYBIOSOURCE INC.
Product Specific References1. Hemler, M.E. 1990. Annu. Rev. Immunol. 114:365.2. Barclay, A.N., M.H. Brown, S.K.A. Law, A.J. McKnight, M.G. Tomlinson, and P.A. van der Merwe, eds. 1997. The Leukocyte Antigens Facts Book, 2nd Edition, CD49f Section, Academic Press, New York, p. 267.3. Tamura, R.N., H.M. Cooper, G. Callo, and V. Quaranta 1991. Proc. Natl. Acad. Sci. USA 88:10183.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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