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Antigenic Specificity | Human CD25 |
Clone | [7G7B6] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a,k |
Format | Protein A purified |
Size | 0.1 mg, 0.5 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: CD25 is the alpha chain of the IL-2 receptor. It is a type I transmembrane protein present on activated T cells, activated B cells, some thymocytes, myeloid precursors, and oligodendrocytes that associates with CD122 to form a heterodimer that can act as a high-affinity receptor for IL-2. The IL2R gene was mapped to 10p15-p14. CD25 is expressed in most B-cell neoplasms, some acute nonlymphocytic leukemias, neuroblastomas, and tumor infiltrating lymphocytes. Its soluble form, called sIL-2R may be elevated in these diseases and is occasionally used to track disease progression. Protein Function: Receptor for interleukin-2. |
Immunogen | Immunogen: Influenza virus stimulated human peripheral blood mononuclear cells. Subcellular Localization: Membrane; Single-pass type I membrane protein. |
Other Names | [Interleukin-2 receptor subunit alpha; IL-2 receptor subunit alpha; IL-2-RA; IL-2R subunit alpha; IL2-RA; TAC antigen; p55; CD25; IL2RA], [IL2RA] |
Gene, Accession # | [CD25], Gene ID: 3559, NCBI: NP_000408.1, UniProt: P01589 |
Catalog # | MBS178894 |
Price | $150, $360 |
Order / More Info | Human CD25 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |