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Antigenic Specificity | GAPDH |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, monkey |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: GAPDH antibody detects endogenous levels of total GAPDH protein from human and monkey.Is unsuitable for MOUSE and RAT, not yet tested in other species. Description: Glyceraldehyde 3 phosphate dehydrogenase (GAPDH) is well known as one of the key enzymes involved in glycolysis. GAPDH is constitutively abundant expressed in almost cell types at high levels, therefore antibodies against GAPDH are useful as loading controls for Western Blotting. Some pathology factors, such as hypoxia and diabetes, increased or decreased GAPDH expression in certain cell types.Function: Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participa |
Immunogen | Immunogen: A synthesized peptide derived from human GAPDH. Subcellular Location: Cytoplasm > Cytosol. Nucleus. Cytoplasm > Perinuclear Region. Membrane. Translocates to the nucleus following S-nitrosylation and interaction with SIAH1, which contains a nuclear localization signal (By similarity). Postnuclear and Perinuclear regions. Predicted Cross Reactivity: Pig, Zebrafish, Horse, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (100%), Zebrafish (100%), Horse (10 |
Other Names | [GAPDH, A1 40 kd subunit, Activator 1 40 kd subunit, G3PD, GAPD, G3pdh, Rfc40, Rf-c 40 kd subunit] |
Gene, Accession # | [GAPDH], Gene ID: 2597, NCBI: NP_001243728.1, UniProt: P04406 |
Catalog # | MBS9600608 |
Price | $170, $225, $280 |
Order / More Info | GAPDH Antibody from MYBIOSOURCE INC. |
Product Specific References | Zhang L, He D, Li K, Liu H, Wang B, Zheng L, Li J; Journal: Biomed Pharmacother. Emodin targets mitochondrial cyclophilin D to induce apoptosis in HepG2 cells. Hui-Fang Wang, Jing-XueMa, Qing-LiShang, Jian-BinAn, Hai-TingChen; Journal: EUR J PHARMACOL. Crocetin inhibits the proliferation, migration and TGF-beta 2-induced epithelial-mesenchymal transition of retinal pigment epithelial cells. |