PARP1 (N-term), 58-87 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | PARP1 (N-term), 58-87 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human (predicted reactivity: hamster, mouse, rat) |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.47 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This PARP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-87 amino acids from the N-terminal region of human PARP1. This gene encodes a chromatin-associated enzyme,poly(ADP-ribosyl)transferase, which modifies various nuclearproteins by poly(ADP-ribosyl)ation. The modification is dependenton DNA and is involved in the regulation of various importantcellular processes such as differentiation, proliferation, andtumor transformation and also in the regulation of the molecularevents involved in the recovery of cell from DNA damage. Inaddition, this enzyme may be the site of mutation in Fanconianemia, and may participate in the pathophysiology of type Idiabetes. |
| Immunogen | n/a |
| Other Names | [Poly [ADP-ribose] polymerase 1; PARP-1; ADP-ribosyltransferase diphtheria toxin-like 1; ARTD1; NAD(+) ADP-ribosyltransferase 1; ADPRT 1; Poly[ADP-ribose] synthase 1; PARP1; ADPRT; PPOL] |
| Gene, Accession # | [PARP1], Gene ID: 142, NCBI: NP_001609.2, UniProt: P09874 |
| Catalog # | MBS9207577 |
| Price | $165, $370 |
| Order / More Info | PARP1 (N-term), 58-87 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Majewski, P.M., et al. J. Biol. Chem. 285(45):34828-34838(2010) Kim, M., et al. Cancer Sci. 101(11):2436-2442(2010) Dong, Y., et al. Cancer Res. 70(20):8088-8096(2010) Krishnakumar, R., et al. Mol. Cell 39(5):736-749(2010) Lee, K.A., et al. Rheumatol. Int. (2010) In press : |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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