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Antigenic Specificity | a1-Antichymotrypsin |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 1 mg |
Concentration | n/a |
Applications | ELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes human alpha1-Antichymotrypsin. a1-Antichymotrypsin (AACT, Alpha1-ACT) is an early-stage acute-phase plasma protein and a serpin that preferentially inactivates chymotrypsin, cathepsin G, and chymase. a1-Antichymotrypsin, a serine protease inhibitor, is tightly associated with amyloid plaques in Alzheimer's disease (AD) and in normal-aged human and monkey brain. Regulation of the serine proteases and serine protease inhibitors plays an important role in neuromuscular differentiation. Prostate specific antigen (PSA), a chymotrypsin-like serine protease, is predominantly complexed to a1-Antichymotrypsin. A higher proportion of serum PSA is complexed to a1-Antichymotrypsin in prostate cancer than in benign prostate hyperplasia. |
Immunogen | Immunogen: Human alpha1-Antichymotrypsin. |
Other Names | a1-Antichymotrypsin (Alpha-1-Antichymotrypsin, AACT, ACT, Growth Inhibiting Protein 24, GIG24, Growth Inhibiting Protein 25, GIG25, Serpin Peptidase Inhibitor Clade A (alpha-1 Antiproteinase, Antitrypsin) Member 3, SERPINA3) |
Gene, Accession # | Gene ID: 5265, NCBI: NP_001121179.1, UniProt: P01009 |
Catalog # | MBS626676 |
Price | $515 |
Order / More Info | a1-Antichymotrypsin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |