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Antigenic Specificity | VDAC1 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG2a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunoblot, Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody recognizes human, mouse and rat VDAC1. It does not cross-react with VDAC2 or VDAC3 (based on evaluation in knock-out mice). VDAC1 (also known as Voltage-dependent anion-selective channel protein 1 and outer mitochondrial membrane protein porin 1) is the outer mitochondrial membrane receptor for hexokinase and BCL2L1. VDAC1 forms a channel through the mitochondrial membrane and is involved in small molecule diffusion, cell volume regulation, and apoptosis. VDAC1 may participate in the formation of the permeability transition pore complex (PTPC) which is responsible for the release of mitochondrial products that trigger apoptosis. |
Immunogen | Immunogen: Fusion protein corresponding to aa 1-283 (full-length) of human VDAC1. This sequence is 98% identical to mouse, 98% identical to rat, and >60% identical to VDAC2 and VCAC3. |
Other Names | [voltage-dependent anion-selective channel protein 1; Voltage-dependent anion-selective channel protein 1; voltage-dependent anion-selective channel protein 1; voltage dependent anion channel 1; Outer mitochondrial membrane protein porin 1; Plasmalemmal porin; Porin 31HL; Porin 31HM], [VDAC1; VDAC1; PORIN; VDAC-1; VDAC; VDAC-1; hVDAC1] |
Gene, Accession # | [VDAC1], Gene ID: 7416, NCBI: NP_003365.1, UniProt: P21796 |
Catalog # | MBS191348 |
Price | $410 |
Order / More Info | VDAC1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |