Human Erk1/2 (MAPK) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human Erk1/2 (MAPK) |
| Clone | [SB46b1] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2a |
| Format | unconjugated |
| Size | 0.5 mg |
| Concentration | n/a |
| Applications | Immunoprecipitation; Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Reacts with human Erk 1 and human Erk21. Erk1 and Erk2 are closely related mitogen activated protein (MAP) kinases which are activated by many growth factors, mitogens and differentiation-promoting agents via a protein kinase cascade. Also known as extracellular signal-regulated kinase 1 and 2, p44/p42 MAP kinases, microtubule-associated protein-2 kinases, myelin basic protein (MBP) kinases or EGF receptor T669 (Ert) kinases 2-5, Erk1 and Erk2 are ubiquitous and abundant, although their relative abundance in specific tissues may vary. The two kinases are nearly 85% identical and have higher identity in the core regions involved in substrate binding 5. Erk1 and Erk2 are activated approximately 1000-fold by phosphorylation within a Thr-Glu-Ty |
| Immunogen | Immunogen: Human recombinant Erk1 and Erk 2 |
| Other Names | n/a |
| Gene, Accession # | n/a |
| Catalog # | MBS670164 |
| Price | $265 |
| Order / More Info | Human Erk1/2 (MAPK) Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1) Boulton, T.G. et al. (1990) Science 249: 64-67.3) Charest, D.L. et al. (1993) Mol Cell. Biol 13: 4679-4690.4) Hardie, G. amd S. Hanks (1995) The Protein Kinase Facts Book, Protein-Serine Kinases, Academic Press Limited, San Diego 418pps.5) Pearson, G. etal. (2001) Endoc. Rev. 22(2): 153-183.6) Xu, B. et al. (2001) J. Biol. Chem. 276(28): 26509-26515. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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