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Antigenic Specificity | Caldesmon (Phospho Ser789) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-Caldesmon (S789) Polyclonal Antibody detects endogenous levels of Caldesmon protein only when phosphorylated at S789. CALD1 encodes a calmodulin- and actin-binding protein (caldesmon 1) that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca (2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca (2+)- dependent inhibition of smooth muscle contraction. Alternative splicing of CALD1 results in multiple transcript variants encoding distinct isoforms. |
Immunogen | Immunogen: Synthesized peptide derived from human Caldesmon around the phosphorylation site of S789 |
Other Names | [Rabbit Caldesmon (phospho Ser789); CALD1; CAD; CDM; Caldesmon] |
Gene, Accession # | [CDM], Gene ID: 800, NCBI: NP_004333.1, UniProt: Q05682 |
Catalog # | MBS9701258 |
Price | $130, $220, $325 |
Order / More Info | Caldesmon (Phospho Ser789) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |