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Antigenic Specificity | Human CD16b |
Clone | [5L11] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Receptors that recognize the Fc portion of IgG are divided into three groups designated Fc gamma RI, RII, and RIII, also known respectively as CD64, CD32, and CD16. In humans each group of receptors is encoded by 2 - 3 closely related genes designated A, B, and C. Fc gamma RI binds IgG with high affinity and functions during early immune responses. Fc gamma RII and RIII are low affinity receptors that recognize IgG as aggregates surrounding multivalent antigens during late immune responses. Different Fc receptors can function as activators, as inhibitors, or as decoy receptors. |
Immunogen | Antibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant CD16b extracellular domain. |
Other Names | [FCGR3B; CD16; FCG3; CD16b; FCGR3; FCR-10; FCRIII; FCRIIIb], [FCGR3B; FCGR3B; CD16; FCG3; CD16b; FCGR3; FCR-10; FCRIII; FCRIIIb; CD16B; FCG3; FCGR3; IGFR3; Fc-gamma RIII; Fc-gamma RIIIb; FcRIII; FcRIIIb] |
Gene, Accession # | [CD16b], Gene ID: 2215, NCBI: NP_000561.3, UniProt: O75015 |
Catalog # | MBS690845 |
Price | $490 |
Order / More Info | Human CD16b Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |