URACIL-DNA GLYCOSYLASE 1 (C-TERMINAL) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityURACIL-DNA GLYCOSYLASE 1 (C-TERMINAL)
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse, rat
Isotypen/a
Formatunconjugated
Size0.1 mg
ConcentrationIgG concentration 1.0mg/ml
ApplicationsWestern Blot (WB)
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DescriptionThis item recognises uracil-DNA glycosylase 1 (UNG1), a member of the uracil-DNA glycosylase and cyclin family. Two isoforms of UNG exist, isoform 1 is expressed in the mitochondria of in skeletal muscle, heart and testicles while isoform 2 (UNG2) is more abundant in proliferating tissues and expressed in the nucleus.. . Uracil residues can be misincorporated into DNA by DNA polymerase or by deamination of cytosine. UNG1 is a major enzyme in base excision repair, excising the misincorporated uracil residues in a process crucial to increasing immunoglobulin diversity. In association with activation-induced cytosine deaminase, UNG is also essential to the generation of strand breaks that initiate class switch recombination.. . UNG is also
ImmunogenImmunogen: 14 amino acid peptide sequence near the amino terminus of human UNG1. Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antisera to human uracil-DNA glycosylase 1 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography. Target Species: Human
Other Names[uracil-DNA glycosylase isoform UNG1; Uracil-DNA glycosylase; uracil-DNA glycosylase; UDG; UNG; uracil-DNA glycosylase 1, uracil-DNA glycosylase 2; uracil-DNA glycosylase], [UNG; UNG; DGU; UDG; UNG1; UNG2; HIGM4; HIGM5; UNG15;]
Gene, Accession #Gene ID: 7374, NCBI: NP_003353.1, UniProt: P13051
Catalog #MBS221489
Price$375
Order / More InfoURACIL-DNA GLYCOSYLASE 1 (C-TERMINAL) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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