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Antigenic Specificity | Human SELP / P-Selectin / CD62P |
Clone | [Psel.KO.2.5] |
Host Species | Mouse |
Reactive Species | human, porcine |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.05 mg |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC - Paraffin), Immunoprecipitation (IP), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes the CD62P cell surface antigen, a 140kD glycoprotein also known as P-selectin. CD62P is expressed by activated platelets and endothelial cells, and plays an important role in adhesive processes between leucocytes and endothelial cells. To produce this mAb, P-selectin-deficient mice were immunized with a pre-B-cell line transfected with human P-selectin cDNA. SELP encodes a 140 kD protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to |
Immunogen | Immunogen Description: CD62P transfected 300.19 cells. |
Other Names | [SELP / P-Selectin / CD62P (clone Psel.KO.2.5) IHC-plus; SELP; CD62P; CD62; GMP-140; GMRP; Granule membrane protein 140; LECAM3; P-selectin; PSEL; CD62P antigen; GMP140; Granulocyte membrane protein; GRMP; PADGEM; Human SELP; P-Selectin; CD62P], [SELP; SELP; CD62; GRMP; PSEL; CD62P; GMP140; LECAM3; PADGEM; GMRP; GRMP; GMP-140; LECAM3; PADGEM] |
Gene, Accession # | [SELP], Gene ID: 6403, NCBI: NP_002996.2 |
Catalog # | MBS245497 |
Price | $530 |
Order / More Info | Human SELP / P-Selectin / CD62P Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |