PARL Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPARL
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
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DescriptionPARL Antibody: PARL is a mitochondrial integral membrane protein and a member of the highly conserved rhomboid superfamily of membrane proteins. PARL is required for the control of apoptosis during postnatal growth and is required for the processing of OPA1, a protein that prevents the release of cytochrome C from the mitochondria in response to apoptotic signals. In lymphocytes and neurons, PARL's association with other proteins, such as the Bcl-2 family-related protein Hax1 and Omi can lead to the proteolytic processing of Omi by PARL, preventing the accumulation of Bax, thereby suppressing apoptosis. Variations in this gene have been associated with increased risk for type 2 diabetes. PARL may also play a role in the progression of Alzhe
ImmunogenImmunogen: PARL antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human PARL. Buffer: PARL Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[PARL; PSARL; PSARL1; RHBDS1; PRO2207; PSENIP2; PSARL; Presenilins-associated rhomboid-like protein; mitochondrial; Mitochondrial intramembrane cleaving protease PARL; Pbeta; presenilin associated, rhomboid-like], [PARL; PARL; PSARL; PSARL1; RHBDS1; PRO2207; PSENIP2; PSARL; Pbeta]
Gene, Accession #[PARL], Gene ID: 55486, NCBI: Q9H300.2, UniProt: Q9H300
Catalog #MBS150055
Price$375
Order / More InfoPARL Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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