JMJD3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityJMJD3
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, monkey
Isotypen/a
Formataffinity purified
Size0.1 mg
Concentration0.50 ug/ul in antibody stabilization buffer
ApplicationsELISA (EIA), Immunoprecipitation (IP), Western Blot (WB)
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DescriptionSpecificity: Cross reactive to isotypes of 3C only. Overview: Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.Structure: Overexpressed in several esophageal squamous cell carcinomas (ESCs).Expression: Nucleus
ImmunogenImmunogen: Synthetic peptide taken within amino acid region 500-550 on JmjC domain-containing histone demthylation protein 3C. Conjugation: Unconjugated
Other Names[Affinity Purified JmjC domain-containing histone demthylation protein 3C; Histone demethylase JMJD3; JmjC domain containing protein 3; Jumonji D3; Jumonji domain containing 3; Kdm6b; KIAA0346; Lysine demethylase 6B]
Gene, Accession #[JMJD3], Gene ID: 23081, NCBI: NP_001140167.1, UniProt: Q9H3R0
Catalog #MBS5400459
Price$390
Order / More InfoJMJD3 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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