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Antigenic Specificity | JMJD3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, monkey |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 0.50 ug/ul in antibody stabilization buffer |
Applications | ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Cross reactive to isotypes of 3C only. Overview: Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.Structure: Overexpressed in several esophageal squamous cell carcinomas (ESCs).Expression: Nucleus |
Immunogen | Immunogen: Synthetic peptide taken within amino acid region 500-550 on JmjC domain-containing histone demthylation protein 3C. Conjugation: Unconjugated |
Other Names | [Affinity Purified JmjC domain-containing histone demthylation protein 3C; Histone demethylase JMJD3; JmjC domain containing protein 3; Jumonji D3; Jumonji domain containing 3; Kdm6b; KIAA0346; Lysine demethylase 6B] |
Gene, Accession # | [JMJD3], Gene ID: 23081, NCBI: NP_001140167.1, UniProt: Q9H3R0 |
Catalog # | MBS5400459 |
Price | $390 |
Order / More Info | JMJD3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |