Hsp90 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Hsp90 |
| Clone | [H9010] |
| Host Species | Mouse |
| Reactive Species | human (beta-specific), rabbit (Beta specific), chicken (Alpha/Beta), rat, dog |
| Isotype | IgG2a |
| Format | ATTO 390 conjugate |
| Size | 0.2 mg |
| Concentration | 1mg/mL |
| Applications | Western Blot (WB), Immunoprecipitation (IP), ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Background Info: Detects ~90kDa proteins corresponding to the molecular mass of hsp90beta. Scientific Background: HSP90 is an abundantly and ubiquitously expressed heat shock protein. It is understood to exist in two principal forms alpha and beta, which share 85% sequence amino acid homology. The two isoforms of Hsp90, are expressed in the cytosolic compartment (1). Despite the similarities, HSP90alpha exists predominantly as a homodimer while HSP90beta exists mainly as a monomer.(2) From a functional perspective, hsp90 participates in the folding, assembly, maturation, and stabilization of specific proteins as an integral component of a chaperone complex. (3-6) Furthermore, Hsp90 is highly conserved between species; having 60% and 78% ami |
| Immunogen | n/a |
| Other Names | [Hsp84; Hsp90; Hsp90 beta; Hsp90B; HspC2; HSPCB], [HSP90AB1; HSP90AB1; HSP84; HSPC2; HSPCB; D6S182; HSP90B; HSP90B; HSPC2; HSPCB; HSP 90; HSP 84; HSP84] |
| Gene, Accession # | Gene ID: 3326, NCBI: NP_031381.2, UniProt: P08238 |
| Catalog # | MBS800389 |
| Price | $500 |
| Order / More Info | Hsp90 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Nemoto T., et al. (1997) J.Biol Chem. 272: 26179-26187. 2. Minami Y., et al. (1991), J.Biol Chem. 266: 10099-10103. 3. Arlander S.J.H., et al. (2003) J Biol Chem 278: 52572- 52577. 4. Pearl H., et al. (2001) Adv Protein Chem 59:157-186. 5. Neckers L., et al. (2002) Trends Mol Med 8:S55-S61. 6. Pratt W., Toft D. (2003) Exp Biol Med 228:111-133. 7. Pratt W., Toft D. (1997) Endocr Rev 18:306-360. 8. Pratt W.B. (1998) Proc Soc Exptl Biol Med 217: 420-434. 9. Whitesell L., et al. (1994) Proc Natl Acad Sci USA 91: 8324- 8328. 10. Barent R. L. (1998) Mol. Endocrinol. 12: 342-354 11. Lo. M.A. (1998) EMBO J. 17: 6879-6887. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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