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Antigenic Specificity | PLD2 (Phospho-Tyr169) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of PLD2 only when phosphorylated at tyrosine 169. Phosphatidylcholine (PC)-specific phospholipases D (PLDs) catalyze the hydrolysis of PC to produce phosphatidic acid and choline. Activation of PC-specific PLDs occurs as a consequence of agonist stimulation of both tyrosine kinase and G protein-coupled receptors. PC-specific PLDs have been proposed to function in regulated secretion, cytoskeletal reorganization, transcriptional regulation, and cell cycle control.Steed P.M., FASEB J. 12:1309-1317(1998).Lopez I., J. Biol. Chem. 273:12846-12852(1998).Divecha N., EMBO J. 19:5440-5449(2000). |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of tyrosine 169(E-N-Y(p)-L-N) derived from Human PLD2. |
Other Names | [PLD 2; PLD1C; choline phosphatase 2] |
Gene, Accession # | [PLD2], Gene ID: 5338, NCBI: NP_001230037.1, UniProt: O14939 |
Catalog # | MBS9413817 |
Price | $200, $255 |
Order / More Info | PLD2 (Phospho-Tyr169) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |