PLD2 (Phospho-Tyr169) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPLD2 (Phospho-Tyr169)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatepitope affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionThe antibody detects endogenous levels of PLD2 only when phosphorylated at tyrosine 169. Phosphatidylcholine (PC)-specific phospholipases D (PLDs) catalyze the hydrolysis of PC to produce phosphatidic acid and choline. Activation of PC-specific PLDs occurs as a consequence of agonist stimulation of both tyrosine kinase and G protein-coupled receptors. PC-specific PLDs have been proposed to function in regulated secretion, cytoskeletal reorganization, transcriptional regulation, and cell cycle control.Steed P.M., FASEB J. 12:1309-1317(1998).Lopez I., J. Biol. Chem. 273:12846-12852(1998).Divecha N., EMBO J. 19:5440-5449(2000).
ImmunogenImmunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of tyrosine 169(E-N-Y(p)-L-N) derived from Human PLD2.
Other Names[PLD 2; PLD1C; choline phosphatase 2]
Gene, Accession #[PLD2], Gene ID: 5338, NCBI: NP_001230037.1, UniProt: O14939
Catalog #MBS9413817
Price$200, $255
Order / More InfoPLD2 (Phospho-Tyr169) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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