Desmin Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Desmin antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Desmin |
| Clone | [D9] |
| Host Species | Mouse |
| Reactive Species | chicken, human, mouse, rabbit, rat, porcine |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Immunohistochemistry (IHC) (frozen), Immunohistochemistry (IHC) (paraffin), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: D9 reacts exclusively with desmin, which is expressed in smooth and striated muscle cells and their tumors e.g. rhabdomyosarcoma and leiomyosarcoma. Desmin (53 kDa) exhibits a high degree of tissue specificity, its expression being predominantly confined to all types of muscle cells (cardiac, skeletal and smooth muscle). Regulation of desmin expression is stage and tissue-specific, since it is induced during terminal development of, for example, skeletal muscle cell differentiation. In skeletal en cardiac muscle cells desmin is localized in the Z-disk region and at the intercalated disk. The expression pattern of desmin in smooth muscle is much more heterogenous. Coexpression of vimentin and desmin has been observed in tumors d |
| Immunogen | Source Note: D9 is a Mouse monoclonal IgG1 antibody derived by fusion of Mouse myeloma cells with spleen cells from a Mouse immunized with desmin isolated from Human leiomyoma. |
| Other Names | [desmin; Desmin; desmin; intermediate filament protein; desmin], [DES; DES; CSM1; CSM2; LGMD2R] |
| Gene, Accession # | Gene ID: 1674, NCBI: NP_001918.3, UniProt: P17661 |
| Catalog # | MBS570113 |
| Price | $415 |
| Order / More Info | Desmin Antibody from MYBIOSOURCE INC. |
| Product Specific References | Council, L., Hameed, O. (2009). Differential expression of immunohistochemical markers in bladder smooth muscle and myofibroblasts, and the potential utility of desmin, smoothelin, and vimentin in staging of bladder carcinoma Modern Pathology 22, 639-50. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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