MBTPS1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | MBTPS1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | 1.0 mg/ml |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody detects endogenous levels of total MBTPS1 protein. Serine protease that catalyzes the first step in the proteolytic activation of the sterol regulatory element-binding proteins (SREBPs). Other known substrates are BDNF, GNPTAB and ATF6. Cleaves after hydrophobic or small residues, provided that Arg or Lys is in position P4. Cleaves known substrates after Arg-Ser-Val-Leu (SERBP-2), Arg-His-Leu-Leu (ATF6), Arg-Gly-Leu-Thr (BDNF) and its own propeptide after Arg-Arg-Leu-Leu. Mediates the protein cleavage of GNPTAB into subunit alpha and beta, thereby participating in biogenesis of lysosomes.Nakajima T., J. Hum. Genet. 45:212-217(2000).Nagase T., DNA Res. 2:37-43(1995).Bechtel S., BMC Genomics 8:399-399(2007). |
| Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from C-terminal of human MBTPS1. |
| Other Names | [Endopeptidase S1P; KIAA0091; MBTP1; MBTPS1; membrane-bound transcription factor peptidase] |
| Gene, Accession # | [MBTPS1], Gene ID: 8720, NCBI: NP_003782.1, UniProt: Q14703 |
| Catalog # | MBS9406420 |
| Price | $200, $255 |
| Order / More Info | MBTPS1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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