PRMT5 (N-term), 76-104 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPRMT5 (N-term), 76-104
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman (predicted reactivity: bovine, monkey)
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.41
ApplicationsWestern Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)
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DescriptionThis PRMT5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 76-104 amino acids from the N-terminal region of human PRMT5. Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Methylates SUPT5H. Mono-and dimethylates arginine residues of myelin basic protein (MBP) in vitro. Plays a role in the assembly of snRNP core particles. May play
Immunogenn/a
Other Names[Protein arginine N-methyltransferase 5; 211-; 72 kDa ICln-binding protein; Histone-arginine N-methyltransferase PRMT5; Jak-binding protein 1; Shk1 kinase-binding protein 1 homolog; SKB1 homolog; SKB1Hs; Protein arginine N-methyltransferase 5; N-terminally processed; PRMT5; HRMT1L5; IBP72; JBP1; SKB1]
Gene, Accession #[PRMT5], Gene ID: 10419, NCBI: NP_001034708.1, UniProt: O14744
Catalog #MBS9213393
Price$165, $370
Order / More InfoPRMT5 (N-term), 76-104 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesAggarwal, P., et al. Cancer Cell 18(4):329-340(2010) Rank, G., et al. Blood 116(9):1585-1592(2010) Cesaro, E., et al. J. Biol. Chem. 284(47):32321-32330(2009) Zhao, Q., et al. Nat. Struct. Mol. Biol. 16(3):304-311(2009) Bruns, A.F., et al. Biol. Chem. 390(1):59-65(2009)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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