Prominin 1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityProminin 1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatunconjugated
Size0.1 mg
Concentration0.50-0.95 ug/ul in antibody stabilization buffer
ApplicationsELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
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DescriptionMay play a role in cell differentiation, proliferation and apoptosis (PubMed:24556617). Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner (PubMed:20818439).
ImmunogenImmunogen: Synthetic peptide taken within amino acid regions 700-730 on CD133 protein. Expression: Isoform 1 is selectively expressed on CD34 hematopoietic stem and progenitor cells in adult and fetal bone marrow, fetal liver, cord blood and adult peripheral blood. Isoform 1 is not detected on other blood cells. Isoform 1 is also expressed in a number of non-lymphoid tissues including retina, pancreas, placenta, kidney, liver, lung, brain and heart. Found in saliva within small membrane particle
Other Names[AC133; CD133; CORD12; Hematopoietic stem cell antigen; MCDR2; MSTP061; RP41; STGD4], [PROM1; PROM1; RP41; AC133; CD133; MCDR2; STGD4; CORD12; PROML1; MSTP061; PROML1]
Gene, Accession #Gene ID: 8842, NCBI: XP_006714037.1
Catalog #MBS540104
Price$390
Order / More InfoProminin 1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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