CD35, Human Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CD35, Human |
| Clone | 31R |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | F, Flow Cytometry (FC/FACS), Immunoassay (IA), Immunoprecipitation (IP), P, Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Product Description: CD35 (CR1) is a type 1 membrane glycoprotein participating in clearance of immune complexes, regulation of autologous complement activation on cell surfaces, and complement-dependent cellular cytotoxicity mediated by leukocytes. CD35 inhibits complement activation by two distinct mechanisms. CD35 is a cofactor for factor I cleavage of C3b, iC3b and C4b. Furthermore CD35 mediates decay-dissociation of C3 and C5 convertases. CD35 is found on erythrocytes, neutrophils, monocytes and dendritic cells. There are four allotypic variants of CD35 (CR1) with different molecular masses: 190 kDa (CR-1A), 220 kDa (CR1-B), 160 kDa (CR1-C) and 250 kDa (CR1-D). The monoclonal antibody 31R binds a single epitope of CR1. |
| Immunogen | n/a |
| Other Names | n/a |
| Gene, Accession # | [CD35] |
| Catalog # | MBS584312 |
| Price | $520 |
| Order / More Info | CD35, Human Antibody from MYBIOSOURCE INC. |
| Product Specific References | Seya, T et al; Rapid purification of human complement receptor type 1 (CD35, CR1). J Biochem Biophys Methods 1996, 32: 69 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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