TrkB Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTrkB
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat, chicken
Isotypen/a
Formataffinity purified
Size0.03 mg, 0.1 mg
Concentration0.2 mg/ml
ApplicationsWestern Blot (WB), Immunoprecipitation (IP), Immunofluorescence (IF)
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DescriptionBackground: Due to the various splice variants, the trk proteins exist as variably glycosylated entities with the major forms having molecular weights of 140-145 kDa, 110 kDa and the unglycosylated form of 80 kDa. trkB contains 33.3% carbohydrate by weight representing modification on 10 of 12 N-glycosylation sites. The primary ligand for trkB is BDNF which induces the phosphorylation of the protein and subsequent binding of PLC-gamma via SH2 domains. TrkB may function to modulate neuronal responses to the neurotrophins acting thromugh trkB such as BDNF.
ImmunogenImmunogen: Synthetic peptide surrounding amino acid 810 of human TrkB
Other Names[NTRK2; GP145-TrkB; TRKB; Trk-B; tyrosine receptor kinase], [Ntrk2; Ntrk2; Tkrb; trkB; TRKB1; trk-B; RATTRKB1; Trkb; Trk-B]
Gene, Accession #[TrkB], Gene ID: 25054, NCBI: NP_001156640.1, UniProt: Q63604
Catalog #MBS840689
Price$150, $360
Order / More InfoTrkB Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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