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Antigenic Specificity | AXIN1 / Axin-1 (C-Terminus) IHC-plus |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human. predicted reactivity: mouse, rat, bovine, chicken, Xenopus, zebrafish (at least 90% immunogen sequence identity) |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mL |
Concentration | 0.76 mg/ml |
Applications | Immunohistochemistry (IHC) Paraffin, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human AXIN. AXIN1 Antibody, Axis inhibitor 1 Antibody, AXIN Antibody, Axin 1 Antibody, Axis inhibition protein 1 Antibody, Fused, mouse, homolog of Antibody, HAxin Antibody, PPP1R49 Antibody, Axin-1 Antibody Description: Component of the beta-catenin destruction complex required for regulating CTNNB1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling. Controls dorsoventral patterning via two opposing effects; down-regulates CTNNB1 to inhibit the Wnt signaling pathway and ventralize embryos, but also dorsalizes embryos by activating a Wnt-independent JNK signaling pathway. In Wnt signaling, probably facilitates the phosphorylation of CTNNB1 and APC by GSK3B. |
Immunogen | Immunogen Description: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Axin 1. Immunogen Type: Synthetic peptide |
Other Names | [Rabbit (IgG) to Human AXIN1 / Axin-1; Human AXIN1 / Axin-1; Axis inhibitor 1; AXIN; Axin 1; Axis inhibition protein 1; Fused; mouse; homolog of; HAxin; PPP1R49; Axin-1], [AXIN1; AXIN1; AXIN; PPP1R49; AXIN; hAxin] |
Gene, Accession # | [AXIN1], Gene ID: 8312, NCBI: O15169.2, UniProt: O15169 |
Catalog # | MBS249583 |
Price | $530 |
Order / More Info | AXIN1 / Axin-1 (C-Terminus) IHC-plus Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |