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Antigenic Specificity | DARPP-32 (pThr34) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | bovine (expected from sequence), chicken (expected from sequence), dog (expected from sequence), human (expected from sequence), monkey (expected from sequence), mouse (expected from sequence) |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB)* |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti Rat DARP-32 (pThr34) antibody recognizes rat DARPP-32, when phosphorylated at threonine 34. DARPP-32 is also known as Protein phosphatase 1 regulatory subunit 1B or Dopamine- and cAMP-regulated neuronal phosphoprotein. DARPP-32 is a 205 amino acid ~32 kDa member of the protein phosphatase inhibitor 1 family. DARPP-32 is principally expressed in striatal medium spiny neurons, and plays a critical role in the regulation of dopaminergic neurotransmission. DARPP-32 can act either as a phosphatase inhibitor or as a kinase inhibitor, depending on its relative state of phosphorylation. Phosphorylation at threonine 34 converts DARPP-32 into an inhibitor of protein phosphatase-1 (PP-1) whilst phosphorylation at threonine 75 switches the |
Immunogen | Buffer Solution: 10mM HEPES pH7.5 Antiserum Preparation: Antisera to phosphorylated rat DARPP-32 were raised by repeated immunisations of rabbits with highly purified antigen. Target Species: Rat |
Other Names | [protein phosphatase 1 regulatory subunit 1B; Protein phosphatase 1 regulatory subunit 1B; protein phosphatase 1 regulatory subunit 1B; dopamine- and cAMP-regulated neuronal phosphoprotein; dopamine- and cAMP-regulated phosphoprotein DARPP-32; neuronal phosphoprotein DARPP-32; protein phosphatase 1, regulatory (inhibitor) subunit 1B; DARPP-32; Dopamine- and cAMP-regulated neuronal phosphoprotein], [Ppp1r1b; Ppp1r1b; Darpp32; Darpp-32] |
Gene, Accession # | [DARPP-32], Gene ID: 360616, NCBI: NP_612530.1, UniProt: Q6J4I0 |
Catalog # | MBS221787 |
Price | $550 |
Order / More Info | DARPP-32 (pThr34) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |