DARPP-32 (pThr34) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityDARPP-32 (pThr34)
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesbovine (expected from sequence), chicken (expected from sequence), dog (expected from sequence), human (expected from sequence), monkey (expected from sequence), mouse (expected from sequence)
Isotypen/a
Formatunconjugated
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)*
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DescriptionRabbit anti Rat DARP-32 (pThr34) antibody recognizes rat DARPP-32, when phosphorylated at threonine 34. DARPP-32 is also known as Protein phosphatase 1 regulatory subunit 1B or Dopamine- and cAMP-regulated neuronal phosphoprotein. DARPP-32 is a 205 amino acid ~32 kDa member of the protein phosphatase inhibitor 1 family. DARPP-32 is principally expressed in striatal medium spiny neurons, and plays a critical role in the regulation of dopaminergic neurotransmission. DARPP-32 can act either as a phosphatase inhibitor or as a kinase inhibitor, depending on its relative state of phosphorylation. Phosphorylation at threonine 34 converts DARPP-32 into an inhibitor of protein phosphatase-1 (PP-1) whilst phosphorylation at threonine 75 switches the
ImmunogenBuffer Solution: 10mM HEPES pH7.5 Antiserum Preparation: Antisera to phosphorylated rat DARPP-32 were raised by repeated immunisations of rabbits with highly purified antigen. Target Species: Rat
Other Names[protein phosphatase 1 regulatory subunit 1B; Protein phosphatase 1 regulatory subunit 1B; protein phosphatase 1 regulatory subunit 1B; dopamine- and cAMP-regulated neuronal phosphoprotein; dopamine- and cAMP-regulated phosphoprotein DARPP-32; neuronal phosphoprotein DARPP-32; protein phosphatase 1, regulatory (inhibitor) subunit 1B; DARPP-32; Dopamine- and cAMP-regulated neuronal phosphoprotein], [Ppp1r1b; Ppp1r1b; Darpp32; Darpp-32]
Gene, Accession #[DARPP-32], Gene ID: 360616, NCBI: NP_612530.1, UniProt: Q6J4I0
Catalog #MBS221787
Price$550
Order / More InfoDARPP-32 (pThr34) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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