Edit |   |
---|---|
Antigenic Specificity | Thioredoxin` |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | caprylic acid ammonium sulfate precipitate |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total Thioredoxin`polyclonal antibody. Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity.Induces the FOS/JUN AP-1 DNA binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity. |
Immunogen | Immunogen: Recombinant Human Thioredoxin` protein |
Other Names | [TXN; TRDX; TRX; TRX1; ATL-derived factor; ADF; Surface-associated sulphydryl protein; SASP; Trx] |
Gene, Accession # | Gene ID: 7295, NCBI: NP_001231867.1, UniProt: P10599 |
Catalog # | MBS9415623 |
Price | $320 |
Order / More Info | Thioredoxin` Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |