CLN5 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CLN5 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: CLN5 antibody detects endogenous levels of total CLN5. Function: Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by controlling the recruitment of retromer complex to the endosomal membrane. Regulates the localization and activation of RAB7A which is required to recruit the retromer complex to the endosomal membrane (PubMed:22431521).Subunit Structure: Interacts with SORT1, RAB5A and RAB7A (PubMed:22431521). Interacts with PPT1, TPP1, CLN3, CLN6, CLN8, ATP5F1A and ATP5F1B (By similarity).Post-translational Modifications: N-glycosylated with both high mannose and complex type sugars. Glycosylation is important for proper f |
| Immunogen | Immunogen: A synthesized peptide Subcellular Location: Lysosome. Tissue Specificity: Ubiquitous. Predicted Cross Reactivity: Pig, Bovine, Sheep, Rabbit, Dog, Chicken Similarity: Pig (91%), Bovine (100%), Sheep (100%), Rabbit (91%), Dog (91%), Chicken (91%) |
| Other Names | [Ceroid lipofuscinosis neuronal 5; Ceroid-lipofuscinosis neuronal protein 5; CLN5; CLN5_HUMAN; NCL; Protein CLN5] |
| Gene, Accession # | [CLN5], Gene ID: 1203, NCBI: NP_006484.1, UniProt: O75503 |
| Catalog # | MBS9605383 |
| Price | $240, $280 |
| Order / More Info | CLN5 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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