Edit |   |
---|---|
Antigenic Specificity | VEGI |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: VEGI Polyclonal Antibody detects endogenous levels of VEGI protein. Tumor necrosis factor ligand superfamily member 15 encoded by TNFSF15 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Two transcript variants encodi |
Immunogen | Immunogen: Synthesized peptide derived from the C-terminal region of human VEGI at AA range: 150-230 |
Other Names | [Rabbit VEGI; TNFSF15; TL1; VEGI; Tumor necrosis factor ligand superfamily member 15; TNF ligand-related molecule 1; Vascular endothelial cell growth inhibitor] |
Gene, Accession # | [VEGI], Gene ID: 9966, NCBI: NP_001191273.1, UniProt: O95150 |
Catalog # | MBS9703361 |
Price | $130, $220, $325 |
Order / More Info | VEGI Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |