Caspase-8 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | Caspase-8 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Caspase-8 Antibody detects endogenous levels of Caspase-8. Apoptosis induced through the CD95 receptor (Fas/APO-1) and tumor necrosis factor receptor 1 (TNFR1) activates caspase-8 and leads to the release of the caspase-8 active fragments, p18 and p10 (1-3). Activated caspase-8 cleaves and activates downstream effector caspases such as caspase-1,-3,-6, and-7. Caspase-3 ultimately elicits the morphological hallmarks of apoptosis, including DNA fragmentation and cell shrinkage. |
| Immunogen | Immunogen: A synthesized peptide derived from human Caspase-8 |
| Other Names | [CASP8; ALPS2B; Apoptotic protease Mch-5; Apoptotic cysteine protease; Caspase-8; CAP4; Caspase 8; MACH; MCH5; Pro Caspase 8; FADD-like ICE; FLICE] |
| Gene, Accession # | [Casp-8], Gene ID: 841, NCBI: NP_001073593.1, UniProt: Q14790 |
| Catalog # | MBS4750075 |
| Price | $335 |
| Order / More Info | Caspase-8 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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