Caspase 12 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Caspase 12 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mg |
| Concentration | 200 ug/ml |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Three distinct signaling pathways lead to programmed cell death. The death receptor and mitochondrion pathways are the mains two pathways, in which the key apoptotic proteases caspase-8 and caspase-9, respectively, are involved. The endoplasmic reticulum stress is the third apoptotic pathway and caspase-12 is involved. Caspase-12 is located to the ER, but not to the cytoplasm or mitochondrion. Caspase-12 is activated by ER stress, including disruption of ER calcium hemeostasis, and mediates ER stress-induced apoptosis. Caspase-12 is localized to the ER with several proteins that are involved in Alzheimer's disease including gamma-secretase presenilin and beta-amyloid precursor protein. Caspase-12 mediates cytotoxicity induced by amyloid-bet |
| Immunogen | Immunogen: Caspase 12 antibody was raised in Rabbit using synthetic peptide corresponding to residues surrounding amino acid 310 of mouse caspase-12 as the immunogen. |
| Other Names | [Rabbit Caspase 12; Caspase 12; Caspase 12; Caspase 12; Caspase 12; Caspase -12; CASP12; Caspase 12; Caspase -12; CASP12P1] |
| Gene, Accession # | [CASP-12], Gene ID: 724039 |
| Catalog # | MBS5311249 |
| Price | $490 |
| Order / More Info | Caspase 12 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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