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Antigenic Specificity | FHL2, Human |
Clone | F4B2-B11 |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 |
Format | Protein G purified |
Size | 0.1 mg |
Concentration | 0.1 mg/ml |
Applications | Immunohistochemistry-Frozen (IHC-F), Immunohistochemistry-Paraffin (IHC-P), Immunofluorescence (IF), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The monoclonal antibody F4B2-B11 reacts specifically with the LIM-only protein FHL2. Five proteins share the same structural organization and a high degree of sequence homology in this group: four and a half LIM domain protein (FHL) 1, FHL2, FHL3, FHL4, and activator of cAMP-responsive element (CRE) modulator (CREM) in testis (ACT). LIM domains are constituted by a conserved cysteine- and histidine-rich structure shaped in two repeated zinc fingers first identified in the proteins encoded by the Lin-11, Isl-1, and Mec-3 genes. The LIM domain has been shown to function as a protein-protein interaction domain, and has often been described in association with other functional protein motifs, such as homeobox and kinase domains. FHL2 seems to b |
Immunogen | n/a |
Other Names | [four and a half LIM domains protein 2; Four and a half LIM domains protein 2; four and a half LIM domains protein 2; LIM domain protein DRAL; aging-associated gene 11; skeletal muscle LIM-protein 3; down-regulated in rhabdomyosarcoma LIM protein; four and a half LIM domains 2; LIM domain protein DRAL; Skeletal muscle LIM-protein 3; SLIM-3], [FHL2; FHL2; DRAL; AAG11; FHL-2; SLIM3; SLIM-3; DRAL; SLIM3; FHL-2; SLIM-3] |
Gene, Accession # | [FHL2], Gene ID: 2274, NCBI: NP_001034581.1 |
Catalog # | MBS584089 |
Price | $720 |
Order / More Info | FHL2, Human Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Samson, T et al; The LIM-only proteins FHL2 and FHL3 interact with alpha- and beta-subunits of the muscle alpha7beta1 integrin receptor. J Biol Chem 2004, 279: 28641 2. Martin, B et al; The LIM-only protein FHL2 interacts with beta-catenin and promotes differentiation of mouse myoblasts. J Cell Biol 2002, 159: 113 |