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Antigenic Specificity | NCOR2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: NCOR2 antibody detects endogenous levels of total NCOR2. Function: Transcriptional corepressor. Mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription. Isoform 1 and isoform 5 have different affinities for different nuclear receptors. Involved in the regulation BCL6-dependent of the germinal center (GC) reactions, mainly through the control of the GC B-cells proliferation and survival.Subunit Structure: Forms a large corepressor complex that contains SIN3A/B and histone deacetylases HDAC1 and HDAC2. This complex associates with the thyroid (TR) and the retinoid acid receptors (RAR) in the absence of ligand, and may sta |
Immunogen | Immunogen: A synthesized peptide derived from human NCOR2 Subcellular Location: Nucleus. Tissue Specificity: Ubiquitous. High levels of expression are detected in lung, spleen and brain. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Sheep, Chicken, Xenopus Similarity: Pig (100%), Zebrafish (82%), Bovine (100%), Horse (100%), Sheep (100%), Chicken (100%), Xenopus (92%) |
Other Names | [CTG 26; CTG repeat protein 26; CTG26; N CoR2; N-CoR2; NCoR 2; Ncor2; NCOR2_HUMAN; Nuclear Receptor Co-Repressor 2; Nuclear receptor corepressor 2; retinoic-acid-receptor-associated corepressor; Silencing Mediator for Retanoid and Thyroid Hormone Receptors; Silencing mediator of retinoic acid and thyroid hormone receptor; SMAP 270; SMAP270; SMRT; SMRTE; SMRTE tau; T3 receptor associating factor; T3 receptor-associating factor; Thyroid retinoic acid receptor associated corepressor; Thyroid-; TNRC 14; TNRC14; TRAC 1; TRAC; TRAC1] |
Gene, Accession # | [NCOR2], Gene ID: 9612, NCBI: NP_001070729.2, UniProt: Q9Y618 |
Catalog # | MBS9609213 |
Price | $240, $280 |
Order / More Info | NCOR2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |