Mouse MAdCAM-1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Mouse MAdCAM-1 |
| Clone | [MECA-367] |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | IgG2a kappa |
| Format | unconjugated |
| Size | 0.5 mg |
| Concentration | n/a |
| Applications | Flow Cytometry; Immunohistochemistry (Frozen Sections); Immunoprecipitation; Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Murine MAdCAM-1 (Mr 58-88 kDa). Mucosal vascular addressin-1 (MAdCAM-1) is a type I transmembrane glycoprotein expressed at high levels on high endothelial venules (HEV) of Peyer's patches and mesenteric lymph nodes, and on flatwalled venules within the gut lamina propria. It is also expressed on sinus-lining cells in the spleen.1-3 The countereceptor or homing receptor for MAdCAM-1 is alpha 4 beta 7 integrin (also known as LPAM-1). MAdCAM-1 is also a facultative ligand for CD62L/L-selectin.4, 5 The monoclonal antibody MECA-367 binds to the first domain of MAdCAM-1 and blocks MAdCAM-1-dependent binding in vitro and lymphocyte homing to Peyer's patch HEV in vivo.1, 2, 4. |
| Immunogen | Immunogen: Endothelial cells isolated from BALB/c mouse mesenteric and peripheral lymph nodes |
| Other Names | [Rat Mouse MAdCAM-1 - Purified, Unlabeled; Rat Mouse MAdCAM-1], [MADCAM1; MADCAM1; MACAM1] |
| Gene, Accession # | Gene ID: 8174, NCBI: NP_570116.2, UniProt: Q13477 |
| Catalog # | MBS673617 |
| Price | $285 |
| Order / More Info | Mouse MAdCAM-1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Streeter, P.R., E.L. Berg, B.T. N. Rouse, R.F. Bargatze, and E.C. Butcher. 1988. Nature 331:41-46.2. Briskin, M.J., L.M. McEvoy, and E.C. Butcher. 1993. Nature 363:461-464.3. Kraal, G., K. Schomagel, P.E. Streeter, B. Holtzmann, and E.C. Butcher. 1995. Am. J. Pathol. 147:763-771.4. Berlin, C., E.L. Berg, M.J. Briskin, et al. 1993. Cell 74:185-195.5. Berg, E.L., L.M. McEvoy, C. Berlin, R.F. Bargatze, and E.C. Bucher. 1993. Nature 366:695-698. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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