Cyclin D1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCyclin D1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionDescription: Rabbit IgG polyclonal antibody for G1/S-specific cyclin-D1(CCND1) detection. Tested with WB in Human. Background: Cyclin D1, also known as CCND1, is a human gene. The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclin D1 encodes the regulatory subunit of a holoenzyme that phosphorylates and inactivates the retinoblastoma protein and promotes progression through the G1-S phase of the cell cycle. Amplification or overexpression of cyclin D1 plays pivotal roles in the development of a subset of human cancers including parathyroid adenoma, breast cancer, colon cancer, lymphoma, melanoma, and pros
ImmunogenImmunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human Cyclin D1 (19-37aa DANLLNDRVLRAMLKAEET), different from the related mouse and rat sequences by two amino acids.
Other Names[G1/S-specific cyclin-D1; cyclin D1; AI327039; B cell ccl/lymphoma 1; B cell CLL/lymphoma 1; B cell leukemia 1; B-cell leukemia 1; B cell lymphoma 1 protein; B-cell lymphoma 1 protein; BCL 1; BCL-1; BCL-1 oncogene; BCL1; BCL1 oncogene; CCND 1; CCND1; CCND1 protein; CCND1/FSTL3 fusion gene, included; CCND1/IGHG1 fusion gene; CCND1/IGHG1 fusion gene, included; CCND1/IGLC1 fusion gene, included; CCND1/PTH fusion gene, included; CCND1_HUMAN; cD1; Cyl 1; D11S287E; G1/S specific cyclin D1; G1/S-specific cyclin-D1; Parathyroid adenomatosis 1; PRAD1; PRAD1 oncogene; U21B31], [CCND1; CCND1; BCL1; PRAD1; U21B31; D11S287E; BCL1; PRAD1; BCL-1]
Gene, Accession #[CCND1], Gene ID: 595, NCBI: P24385.1, UniProt: P24385
Catalog #MBS177038
Price$280
Order / More InfoCyclin D1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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