IRAK-1/IRAK1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | IRAK-1/IRAK1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: No cross reactivity with other proteins. Description: Rabbit IgG polyclonal antibody for IRAK-1/IRAK1 detection. Tested with WB, IHC-P in Human; Mouse; Rat.Background: Interleukin-1 receptor-associated kinase 1, also called IRAK1, is an enzyme that in humans is encoded by the IRAK1 gene. By radiation hybrid analysis, this gene is mapped to chromosome Xq28. Serine/threonine-protein kinase plays a critical role in initiating innate immune response against foreign pathogens. This gene involved in Toll-like receptor (TLR) and IL-1R signaling pathways. This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) up |
| Immunogen | Immunogen: A synthetic peptide corresponding to a sequence of human IRAK-1/IRAK1 (NRNARVADLVHILTHLQLLRARD). |
| Other Names | [Interleukin-1 receptor-associated kinase 1; IRAK-1; IRAK1; IRAK] |
| Gene, Accession # | [IRAK-1], Gene ID: 3654, NCBI: NP_001020413.1, UniProt: P51617 |
| Catalog # | MBS1752848 |
| Price | $315 |
| Order / More Info | IRAK-1/IRAK1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Chassin, C., Kocur, M., Pott, J., Duerr, C. U., Gutle, D., Lotz, M., Hornef, M. W. miR-146a mediates protective innate immune tolerance in the neonate intestine. Cell Host Microbe 8: 358-368, 2010. 2. Jacob, C. O., Zhu, J., Armstrong, D. L., Yan, M., Han, J., Zhou, X. J., Thomas, J. A., Reiff, A., Myones, B. L., Ojwang, J. O., Kaufman, K. M., Klein-Gitelman, M., and 17 others. Identification of IRAK1 as a risk gene with critical role in the pathogenesis of systemic lupus erythematosus. Proc. Nat. Acad. Sci. 106: 6256-6261, 2009. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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