RNF144B (Center), 90-118 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | RNF144B (Center), 90-118 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This RNF144B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-118 amino acids from the Central region of human RNF144B. E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, thereby promoting their degradation. Induces apoptosis via a TP53/p53-dependent but caspase-independent mechanism. However, its overexpression also produces a decrease of the ubiquitin-dependent stability of BAX, a pro-apoptotic protein, ultimately leading to protection of cell death; But, it is not an anti-apoptotic protein per se. |
| Immunogen | n/a |
| Other Names | [E3 ubiquitin-protein ligase RNF144B; 632-; IBR domain-containing protein 2; RING finger protein 144B; p53-inducible RING finger protein; RNF144B; IBRDC2; P53RFP] |
| Gene, Accession # | [RNF144B], Gene ID: 255488, NCBI: NP_877434.2, UniProt: Q7Z419 |
| Catalog # | MBS9204093 |
| Price | $165, $370 |
| Order / More Info | RNF144B (Center), 90-118 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Sayan, B.S., et al. Proc. Natl. Acad. Sci. U.S.A. 107(29):12877-12882(2010) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Benard, G., et al. EMBO J. 29(8):1458-1471(2010) Markson, G., et al. Genome Res. 19(10):1905-1911(2009) van Wijk, S.J., et al. Mol. Syst. Biol. 5, 295 (2009) : |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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