TOX3 / TNRC9 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | TOX3 / TNRC9 |
| Clone | [TOX3/1124] |
| Host Species | Mouse |
| Reactive Species | human. |
| Isotype | IgG1, kappa |
| Format | unconjugated |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: It recognizes a 63kDa protein, which is identified as TOX3. It contains a high mobility group (HMG)-box, which regulates Ca2+-dependent transcription in neurons through interaction with the cAMP-response-element-binding protein (CREB). TOX3 appears to be associated with breast cancer susceptibility and is expressed downstream of a cytoprotective cascade together with CITED1, a transcriptional regulator that does not bind directly to DNA. TOX3 is predominantly expressed in the brain and forms homodimers. TOX3 overexpression protects neuronal cells from cell death caused by endoplasmic reticulum stress or BAX overexpression through the induction of anti-apoptotic transcripts and repression of pro-apoptotic transcripts. |
| Immunogen | Immunogen: Recombinant fragment (139 Amino acid residues around aa 200-400) of human TOX3 protein |
| Other Names | [TOX3; CAG trinucleotide repeat-containing gene F9 protein; CAGF9; TOX high mobility group box family member 3; Trinucleotide repeat containing 9 (TNRC9)], [TOX3; TOX3; CAGF9; TNRC9; CAGF9; TNRC9] |
| Gene, Accession # | [TOX3], Gene ID: 27324, NCBI: NP_001073899.2, UniProt: O15405 |
| Catalog # | MBS439154 |
| Price | $190, $340, $340 |
| Order / More Info | TOX3 / TNRC9 Antibody from MYBIOSOURCE INC. |
| Product Specific References | O'Flaherty, E., et al. 2003. TOX defines a conserved subfamily of HMG-box proteins. BMC Genomics 4: 13. Smid, M., et al. 2006. Genes associated with breast cancer metastatic to bone. J. Clin. Oncol. 24: 2261-2267. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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