Edit |   |
---|---|
Antigenic Specificity | BSPRY |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 0.9mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total BSPRY protein. BSPRY (B-box and SPRY domain containing) is a 402 amino acid protein that localizes to both the membrane and the cytoplasm and contains one B box-type zinc finger and one B30.2/SPRY domain. Existing as two alternatively spliced isoforms, BSPRY interacts with TRPV5 and TRPV6 and is thought to regulate the transport of calcium across the epithelium, probably by inhibiting the activity of TRPV proteins. The gene encoding BSPRY maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. N |
Immunogen | Immunogen: Synthetic peptide of human BSPRY Immunogen Type: Peptide |
Other Names | [B box and SPRY domain-containing protein isoform 1; B box and SPRY domain-containing protein; B box and SPRY domain-containing protein; B-box and SPRY domain containing] |
Gene, Accession # | [BSPRY], Gene ID: 54836, NCBI: NP_001304872.1, UniProt: Q5W0U4 |
Catalog # | MBS9417415 |
Price | $255 |
Order / More Info | BSPRY Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |