ATF4 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityATF4
Clone[S360A-24]
Host SpeciesMouse
Reactive Specieshuman, rat
IsotypeIgG2a
Formatfluorescein (FITC) conjugate
Size0.1 mg
Concentration1mg/mL
ApplicationsWestern Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC)
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DescriptionBackground Info: Detects 60 kDa protein. Does not cross-react with ATF5 Scientific Background: Cyclic AMP-dependent transcription factor ATF-4 (ATF4) is a basic leucine-zipper (bZip) transcription factor, which regulates amino acid metabolism, DNA damage repair, chromatin remodeling, and apoptosis in response to cellular and ER stress. ATF4 works with various proteins, such as C/EBP homology protein (CHOP), aspargine synthetase (ASNS), and cAMP response element (CRE) among others to mediate cellular stress. ATF4 also regulates glucose homeostasis by suppressing beta-cell proliferation and insulin production. Furthermore, ATF4 targets the histone demethylase JMJD3 to alter chromatin structure and enhance gene transcription in response to ami
Immunogenn/a
Other Names[Activating Transcription Factor 4; ATF 4; ATF4 protein; cAMP-dependent transcription factor ATF-4; cAMP-responsive element-binding protein 2; CREB 2; CREB-2; CREB2; Cyclic AMP dependent transcription factor ATF 4], [ATF4; ATF4; CREB2; TXREB; CREB-2; TAXREB67; CREB2; TXREB; cAMP-dependent transcription factor ATF-4; CREB-2; cAMP-responsive element-binding protein 2; TaxREB67]
Gene, Accession #Gene ID: 468, NCBI: NP_001666.2, UniProt: P18848
Catalog #MBS800297
Price$430
Order / More InfoATF4 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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