IRF3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityIRF3
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
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DescriptionIRF3 Antibody: Interferons (IFN)s are involved in a multitude of immune interactions during viral infections and play a major role in both the induction and regulation of innate and adaptive antiviral mechanisms. During infection, host-virus interactions signal downstream molecules such as transcription factors such as IFN regulatory factor-3 (IRF3) which can act to stimulate transcription of IFN-alpha/beta genes. IRF3 is present in an inactive form in the cytoplasm of most cells. Following viral infection, IRF3 can be activated by IκB kinase-ε and TANK-binding kinase 1 (TBK1), whereupon IRF3 translocates to the nucleus. IRF3 can also be activated by stimulation of toll-like receptor 3 (TLR3) by dsRNA. IRF3 exists as at least two
ImmunogenImmunogen: IRF3 antibody antibody was raised against a peptide corresponding to 14 amino acids near the center of human IRF3. Buffer: IRF3 Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[IRF3; Interferon regulatory factor 3; IRF-3; interferon regulatory factor 3], [IRF3; IRF3; IRF-3]
Gene, Accession #[IRF3], Gene ID: 3661, NCBI: NP_001562, UniProt: Q14653
Catalog #MBS150587
Price$375
Order / More InfoIRF3 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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