WAVE2 (Central region) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | WAVE2 (Central region) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, rat, mouse |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | ELISA, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody was affinity purified using WAVE2 (Central region) peptide (without carrier). The antibody detects a 78 kDa* protein corresponding to the molecular mass of WAVE2 on SDS-PAGE immunoblots of rat PC12 cells. The Wiskott-Aldrich syndrome protein (WASP) family is involved in various pathways that regulate actin cytoskeletal organization. This family includes WASP, N-WASP, and three WAVE/SCAR isoforms, WAVEs 1, 2, and 3. WAVE proteins play key roles in actin-mediated cell events, such as membrane ruffling and lamellipodia formation. WAVEs contain an Nterminal WAVE homology domain, a basic domain, a Proline-rich region, and carboxy terminal verprolin, cofilin, and acidic (VCA) region. WAVEs are thought to act downstream of the Rac GT |
| Immunogen | Immunogen: A synthetic peptide (coupled to KLH) corresponding to amino acid residues in the central region of human WAVE2. This sequence has highhomology with similar regions in rat and mouse WAVE2, and has low homology to similar regions in WAVE1 and WAVE3. |
| Other Names | [Wiskott-Aldrich syndrome verproline-homologous protein 2; Scar2; WASF2], [WASF2; WASF2; SCAR2; WAVE2; dJ393P12.2] |
| Gene, Accession # | Gene ID: 10163, NCBI: NP_001188333.1, UniProt: Q05BU7 |
| Catalog # | MBS472070 |
| Price | $385 |
| Order / More Info | WAVE2 (Central region) Antibody from MYBIOSOURCE INC. |
| Product Specific References | • Ardern, H. et al. (2006) Cell Motil. Cytosk. 63:6.• Leng, Y. et al. (2005) PNAS 102(4):1098.• Suetsugu, S. et al. (1999) Bioch. Biophs. Res. Comm. 260:296.• Miki, H. et al. (1999) J Biol. Chem. 274(39):27605. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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