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Antigenic Specificity | HtrA2 (Phospho Ser212) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-HtrA2 (S212) Polyclonal Antibody detects endogenous levels of HtrA2 protein only when phosphorylated at S212. HTRA2 encodes a serine protease. The HtrA serine peptidase 2 has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. |
Immunogen | Immunogen: Synthesized peptide derived from human HtrA2 around the phosphorylation site of S212 |
Other Names | [Rabbit HtrA2 (phospho Ser212); HTRA2; OMI; PRSS25; Serine protease HTRA2; mitochondrial; High temperature requirement protein A2; HtrA2; Omi stress-regulated endoprotease; Serine protease 25; Serine proteinase OMI] |
Gene, Accession # | [HTRA2], Gene ID: 27429, NCBI: NP_037379.1, UniProt: O43464 |
Catalog # | MBS9705202 |
Price | $130, $220, $325 |
Order / More Info | HtrA2 (Phospho Ser212) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |