STAT1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySTAT1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatepitope affinity purified
Size0.1 mg
Concentration1ug/ul
ApplicationsImmunohistochemistry (IHC)
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DescriptionSpecificity: STAT1 (phospho-Ser727) antibody detects endogenous levels of STAT1 only when phosphorylated at serine 727. This gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct
ImmunogenImmunogen: The antiserum was produced against synthesized phosphopeptide derived from human STAT1 around the phosphorylation site of serine 727 (P-M-SP-P-E).
Other Names[Stat1; Signal transducer and activator of transcription 1; signal transducer and activator of transcription 1; signal transducer and activator of transcription 1], [Stat1; Stat1; AA408197; 2010005J02Rik]
Gene, Accession #[STAT1], Gene ID: 20846, NCBI: AAA19454.1
Catalog #MBS417090
Price$325
Order / More InfoSTAT1 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesYuan ZM, et al. (1999) Nature.399 (6738): 814-817.Schindler C, et al. (1992) Proc. Natl. Acad. Sci. U.S.A 89:7836-7839Strausberg R.L (2002). Proc. Natl. Acad. Sci. U.S.A. 99:16899-16903.Quelle F.W., (1995) J. Biol. Chem. 270:20775-20780
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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