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Antigenic Specificity | STAT1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.1 mg |
Concentration | 1ug/ul |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: STAT1 (phospho-Ser727) antibody detects endogenous levels of STAT1 only when phosphorylated at serine 727. This gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct |
Immunogen | Immunogen: The antiserum was produced against synthesized phosphopeptide derived from human STAT1 around the phosphorylation site of serine 727 (P-M-SP-P-E). |
Other Names | [Stat1; Signal transducer and activator of transcription 1; signal transducer and activator of transcription 1; signal transducer and activator of transcription 1], [Stat1; Stat1; AA408197; 2010005J02Rik] |
Gene, Accession # | [STAT1], Gene ID: 20846, NCBI: AAA19454.1 |
Catalog # | MBS417090 |
Price | $325 |
Order / More Info | STAT1 Antibody from MYBIOSOURCE INC. |
Product Specific References | Yuan ZM, et al. (1999) Nature.399 (6738): 814-817.Schindler C, et al. (1992) Proc. Natl. Acad. Sci. U.S.A 89:7836-7839Strausberg R.L (2002). Proc. Natl. Acad. Sci. U.S.A. 99:16899-16903.Quelle F.W., (1995) J. Biol. Chem. 270:20775-20780 |