SMYD2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySMYD2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunofluorescence (IF)
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DescriptionProtein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically methylates histone H3 'Lys-4' (H3K4me) and dimethylates histone H3 'Lys-36' (H3K36me2). Shows even higher methyltransferase activity on p53/TP53. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates RB1 at 'Lys-860'.
ImmunogenImmunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human SMYD2 (NP 064582.2).
Other Names[KMT3C; HSKM-B; ZMYND14]
Gene, Accession #[SMYD2], Gene ID: 56950, NCBI: Q9NRG4.2, UniProt: Q9NRG4
Catalog #MBS8546138
Price$280
Order / More InfoSMYD2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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